• High Quality Decitabine / 5-Aza-2′ -Deoxycytidine CAS 2353-33-5 Treatment of Myelodysplastic Syndrome
  • High Quality Decitabine / 5-Aza-2′ -Deoxycytidine CAS 2353-33-5 Treatment of Myelodysplastic Syndrome
  • High Quality Decitabine / 5-Aza-2′ -Deoxycytidine CAS 2353-33-5 Treatment of Myelodysplastic Syndrome
  • High Quality Decitabine / 5-Aza-2′ -Deoxycytidine CAS 2353-33-5 Treatment of Myelodysplastic Syndrome
  • High Quality Decitabine / 5-Aza-2′ -Deoxycytidine CAS 2353-33-5 Treatment of Myelodysplastic Syndrome
  • High Quality Decitabine / 5-Aza-2′ -Deoxycytidine CAS 2353-33-5 Treatment of Myelodysplastic Syndrome

High Quality Decitabine / 5-Aza-2′ -Deoxycytidine CAS 2353-33-5 Treatment of Myelodysplastic Syndrome

CAS No.: 2353-33-5
Formula: C8h12n4o4
EINECS: 219-089-4
Environmental Protection: Yes
Certification: SGS
Color: White
Samples:
US$ 1/Piece 1 Piece(Min.Order)
| Request Sample
Gold Member Since 2023

Suppliers with verified business licenses

Hubei, China
Importers and Exporters
The supplier has import and export rights
High Repeat Buyers Choice
More than 50% of buyers repeatedly choose the supplier
Fast Delivery
The supplier can deliver the goods within 15 days
Flexible Customization
The supplier provides Flexible customization services for your Personalized requirements
to see all verified strength labels (12)
  • Overview
  • Product Description
  • Detailed Photos
  • Packaging & Shipping
  • Company Profile
  • FAQ
Overview

Basic Info.

Model NO.
N/A
Appearance
Powder
Package
Foil Pouch/Paper Drum
Feature
Powder
Price
Negotiable
Sample
Yes
MOQ
Negotiable
Transport Package
as Request
Specification
as request
Origin
China
Production Capacity
100000ton

Product Description

Product Description
 

High Quality Decitabine / 5-aza-2'-deoxycytidine CAS 2353-33-5 Treatment Of Myelodysplastic Syndrome

Product Name:    5-Aza-2'-deoxycytidine
Synonyms:    4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one;5-Aza-2'-deoxycytidine,98+%;4-Amino-1-(2-deoxy-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one;Decitabine(NSC127716);4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-s-triazin-2(1h)-on;4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-s-triazin-2(1h)-one;5-azadeoxycytidine;5-triazin-2(1h)-one,4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-3
CAS:    2353-33-5
MF:    C8H12N4O4
MW:    228.21
EINECS:    219-089-4
Product Categories:    Inhibitors;Deoxycytidine;API;Bases & Related Reagents;Nucleotides;Anti-cancer&immunity;analog of cytosine;Intermediates & Fine Chemicals;Pharmaceuticals;Epigenetics;Inhibitor
Mol File:    2353-33-5.mol


5-Aza-2'-deoxycytidine nucleoside, also known as decitabine and 5-aza-2′-deoxycytidine, is a natural adenosine analogue of 2′-deoxycytidine, which inhibits tumor cell proliferation as well as prevents the development of drug resistance by inhibiting DNA methyltransferase and reducing DNA methylation, and is the strongest known specific inhibitor of DNA methylation, belongs to S-phase cell cycle specific drugs, and is indicated for the treatment of myelodysplastic syndrome (MDS for short).



Decitabine / 5-aza-2'-deoxycytidine CAS 2353-33-5 of Chemical Properties
Melting point     ~200 °C (dec.)
alpha     D22 +68.5° (30 min) +57.8° (6 hr) (c = 0.5 in water)
Boiling point     370.01°C (rough estimate)
density     1.3771 (rough estimate)
refractive index     1.6590 (estimate)
storage temp.     Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility     acetic acid/water (1:1): 50 mg/mL
pka    14.02±0.60(Predicted)
form     Powder
color     White to Off-white
Merck     14,2853
BRN     617982
Stability:    Stable. May be light or air sensitive. Incompatible with strong oxidizing agents.
InChIKey    XAUDJQYHKZQPEU-KVQBGUIXSA-N
CAS DataBase Reference    2353-33-5(CAS DataBase Reference)
EPA Substance Registry System    5-Aza-2'-deoxycytidine (2353-33-5)

Function and Application of Decitabine / 5-aza-2'-deoxycytidine CAS 2353-33-5
1. 5-Aza-2′-deoxycytidine has been used as a demethylating agent in breast cancer cell line, chromatin, DNA and promoter region of p16 gene.
2. Decitabine / 5-aza-2'-deoxycytidine
 used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines.
3. Decitabine is a potent inhibitor of DNA methylation with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively
Detailed Photos

 

High Quality Decitabine / 5-Aza-2′ -Deoxycytidine CAS 2353-33-5 Treatment of Myelodysplastic Syndrome
 
 
Packaging & Shipping
Liquid:
200L Plastic or Iron Drum.
20L, 10L, 5L HDPE, FHDPE, CO-EX, PET Drum
1L, 500mL, 250ml 200mL, 100mL, 50mL HDPE, FHDPE, CO-EX, PET, Aluminum Bottle, Shrink film, Measurement cup.
Solid:
25kg, 20kg, 10kg, 5kg, fibre drum, PP Bag, Craft Paper Bag,
1kg, 500g, 200g, 100g, 50g, 20g Aluminum Foil Bag, Soluble Bag.
The package can be made as the customer's requirement.
Supply Ability(Kilograms):1000 Ton/Tons per Year
Lead Time:within 20 days or as customs' requirement.
Delivery time 3-5 working days
Packaging Typically inside 25kgs or client's requirement ,with food grade plastic inner bag , outside paper-drum .
Net Weight: 25kgs/Drum, Gross Weight: 28kgs/Drum
Drum Size & Volume: I.D.42cm×H52cm, 0.08m³/ Drum

High Quality Decitabine / 5-Aza-2′ -Deoxycytidine CAS 2353-33-5 Treatment of Myelodysplastic SyndromeHigh Quality Decitabine / 5-Aza-2′ -Deoxycytidine CAS 2353-33-5 Treatment of Myelodysplastic Syndrome

Company Profile

Hubei Marvel Biopharmaceutical Co., Ltd. is located in Wuhan, Hubei Province, which is a water, land, and air transportation hub. It is a company dedicated to the development and sales of fine chemicals, pesticide raw materials, and other products.
The company is committed to developing into a powerful brand company with independent import and export management rights. Its innovative and breakthrough products not only make Marvel Pharmaceutical a leader in the industry domestically, but also enjoy a high reputation internationally. Always adhere to the business philosophy of "customer satisfaction and enterprise development", build a bridge with customers with the spirit of integrity and dedication, and serve customers better, faster, and more accurately.
The company has independent import and export management rights and an excellent sales team. With the diligent efforts of all employees, we have opened up a vast market for the company. The company's products sell well throughout the country and are exported to countries and regions such as Europe, America, Southeast Asia, and Africa. The number of customers served each year is over 2000, winning unanimous recognition and praise from our customers.
High Quality Decitabine / 5-Aza-2′ -Deoxycytidine CAS 2353-33-5 Treatment of Myelodysplastic Syndrome


High Quality Decitabine / 5-Aza-2′ -Deoxycytidine CAS 2353-33-5 Treatment of Myelodysplastic Syndrome

FAQ


Q1: May I get one sample before placing order?
Re: Yes, Sample are available. For normal products, samples are for free and you just need to bear the freight; For those high value products, you just need to freight and certain product cost. When we both cooperate for some times or when you are our VIP customer, free sample will be offered when you need.

Q2: Which payment is available for your company?
Re: T/T, L/C or Alibaba trade insurance. You can choose the one which is convenient for you.

Q3: How and when can I get my goods after payment?
Re: For small quantity products, they will be delivered to you by international courier(DHL, FedEx, TNT etc.)
or by air. Usually it will cost 3-5days that you can get the goods after delivery.For large quantity products,
shipping by see is worthwhile.It will cost days to weeks to come to your destination port, which depends on
where the port is.

Q4: Is there any possible to use my appointed label or package?
Re: Yes. If needed, we'd like to use label or package according to your requirement.

Q5: How can you guarantee the goods you offer is qualified?
Re: We always believe honesty and responsibility are basis of one company, so whatever products we provide for you all are qualified. We will have goods tested and provide COA before delivery for sure.



 

Send your message to this supplier

*From:
*To:
*Message:

Enter between 20 to 4,000 characters.

This is not what you are looking for? Post a Sourcing Request Now

You Might Also Like

Gold Member Since 2023

Suppliers with verified business licenses

Trading Company
Export Year
2024-05-06
Import & Export Mode
Have Own Export License